Gene

mgp

ID
ZDB-GENE-060928-1
Name
matrix Gla protein
Symbol
mgp Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Predicted to localize to collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in arteriosclerosis; calcinosis; and myocardial infarction. Is expressed in caudal fin; gill filament; sensory system; skeletal system; and trabecular layer. Orthologous to human MGP (matrix Gla protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mgp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Keutel syndrome 245150
Associated With mgp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
Family IPR027118 Matrix Gla protein
Homologous_superfamily IPR035972 Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
Domain Details Per Protein
Protein Length Gamma-carboxyglutamic acid-rich (GLA) domain Gamma-carboxyglutamic acid-rich (GLA) domain superfamily Matrix Gla protein
UniProtKB:F8W542 112
UniProtKB:Q6YND0 105
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations