ZFIN ID: ZDB-GENE-060908-3
Gene Name: sodium channel, voltage gated, type V-like, alpha b
Gene Symbol: scn5lab    Nomenclature History

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Previous Names: scn12ab, scn5Lab (1), zscn7 (1), wu:fi13c05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits voltage-gated sodium channel activity. Involved in heart looping and regulation of heart contraction. Predicted to localize to voltage-gated sodium channel complex. Is expressed in gill; heart; nervous system; skeletal muscle; and somite.
Genome Resources: Alliance (1),  Gene:566868 (1),  Ensembl(GRCz11):ENSDARG00000102312 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10223 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10300 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32502 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32503 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39466 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44202 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-scn5lab N/A 4
    MO2-scn5lab N/A 1
    DISEASE ASSOCIATED WITH scn5lab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH scn5lab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart looping (more)
    Cellular Component voltage-gated sodium channel complex (more)
    Molecular Function voltage-gated sodium channel activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM scn5lab No data available
    MARKER RELATIONSHIPS
    scn5lab Encodes: [EST] fi13c05
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045123 (1) 5865 nt
    Genomic GenBank:CABZ01073562 (1) 19348 nt
    Polypeptide UniProtKB:A0A0G2KYI1 (1) 1954 aa
    Sequence Information (all 44)
    ORTHOLOGY for scn5lab ( Chr: 24 )
    CITATIONS (28)