Gene

scn12aa

ID
ZDB-GENE-060908-2
Name
sodium channel, voltage gated, type XII, alpha a
Symbol
scn12aa Nomenclature History
Previous Names
  • scn5Laa (1)
  • zscn6 (1)
  • zmp:0000001002
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have voltage-gated sodium channel activity. Involved in heart looping and regulation of heart contraction. Predicted to localize to voltage-gated sodium channel complex. Is expressed in nervous system and pericardial region.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Chopra et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With scn12aa Human Ortholog
No data available
Associated With scn12aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR005821 Ion transport domain
Domain IPR010526 Sodium ion transport-associated domain
Domain IPR024583 Voltage-gated Na+ ion channel, cytoplasmic domain
Domain IPR044564 Voltage-gated sodium channel alpha subunit, inactivation gate
Family IPR001696 Voltage gated sodium channel, alpha subunit
Family IPR043203 Voltage-gated cation channel calcium and sodium
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain IQ motif, EF-hand binding site Sodium ion transport-associated domain Voltage-dependent channel domain superfamily Voltage-gated cation channel calcium and sodium Voltage-gated Na+ ion channel, cytoplasmic domain Voltage gated sodium channel, alpha subunit Voltage-gated sodium channel alpha subunit, inactivation gate
UniProtKB:Q20JQ5 1932
UniProtKB:A0A8M3B7Z1 1940
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations