Gene

fgf10b

ID
ZDB-GENE-060828-1
Name
fibroblast growth factor 10b
Symbol
fgf10b Nomenclature History
Previous Names
  • fgf25 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have fibroblast growth factor receptor binding activity and growth factor activity. Involved in animal organ development and ectodermal placode development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Is expressed in digestive system; lateral line system; mesoderm; pronephros; and tail bud. Orthologous to human FGF10 (fibroblast growth factor 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgf10b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aplasia of lacrimal and salivary glands Alliance Aplasia of lacrimal and salivary glands 180920
LADD syndrome Alliance LADD syndrome 149730
Associated With fgf10b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002209 Fibroblast growth factor family
Family IPR028252 Fibroblast growth factor 10
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Fibroblast growth factor 10 Fibroblast growth factor family
UniProtKB:A0A0R4ITI2 191
UniProtKB:Q1XG75 187
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations