Gene

nprl2

ID
ZDB-GENE-060825-93
Name
NPR2 like, GATOR1 complex subunit
Symbol
nprl2 Nomenclature History
Previous Names
  • im:6900399
  • tusc4
  • zgc:153630
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to be involved in several processes, including cellular response to starvation; negative regulation of TOR signaling; and regulation of autophagosome assembly. Predicted to localize to GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL2 (NPR2 like, GATOR1 complex subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nprl2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Epilepsy, familial focal, with variable foci 2 617116
Associated With nprl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR009348 Nitrogen permease regulator 2
Domain Details Per Protein
Protein Length Nitrogen permease regulator 2
UniProtKB:Q0P403 379
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations