ZFIN ID: ZDB-GENE-060825-37
Gene Name: SET domain containing (lysine methyltransferase) 8a
Gene Symbol: setd8a

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Previous Names: wu:fj33f02, zgc:153719

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
  blastoderm, blastodisc, brain, intermediate cell mass of mesoderm (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-setd8a (1), MO2-setd8a (1), MO3-setd8a (1)
PHENOTYPE
Data: 3 figures from Li et al., 2011
Observed in: histone methyltransferase activity (H4-K20 specific), post-vent region, shield, telencephalon (all 5) expand
DISEASE ASSOCIATED WITH setd8a HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component chromosome (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR016858 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS51571 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM setd8a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    setd8aEncodes: [EST] fj33f02
    [cDNA] MGC:153719 (1) (order this), MGC:192791 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045349 (1) 1644bp
    Genomic GenBank:CU694500 (1) 35886bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXW2 (1) 344aa
    Sequence Clusters UniGene:122337 (1)
    Sequence Information (all 22)
    OTHER setd8a GENE PAGES
  • Gene:751629 (1)
  • Ensembl(GRCz10):ENSDARG00000105231 (1)
  • ORTHOLOGY for setd8a (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human KMT5A 12
  • Gene:387893
  • OMIM:607240
  • HGNC:29489
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Kmt5a 5
  • MGI:1915206
  • Gene:67956
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)