ZFIN ID: ZDB-GENE-060825-37
Gene Name: SET domain containing (lysine methyltransferase) 8a
Gene Symbol: setd8a
Previous Names: wu:fj33f02, zgc:153719
Location: Chr: 10 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
  blastoderm, blastodisc, brain, intermediate cell mass of mesoderm (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-setd8a (1), MO2-setd8a (1), MO3-setd8a (1)
PHENOTYPE
Data: 3 figures from Li et al., 2011
Observed in: histone methyltransferase activity (H4-K20 specific), post-vent region, shield, telencephalon (all 5) expand
DISEASE ASSOCIATED WITH setd8a HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component chromosome (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR016858 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS51571 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM setd8a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    setd8aEncodes: [EST] fj33f02
    [cDNA] MGC:153719 (1) (order this), MGC:192791 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045349 (1) 1644bp
    Genomic GenBank:CU694500 (1) 35886bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXW2 (1) 344aa
    Sequence Clusters UniGene:122337 (1)
    Sequence Information (all 22)
    OTHER setd8a GENE PAGES
  • Gene:751629 (1)
  • Ensembl(GRCz10):ENSDARG00000105231 (1)
  • ORTHOLOGY for setd8a (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human KMT5A 12
  • Gene:387893
  • OMIM:607240
  • HGNC:29489
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Setd8 5
  • MGI:1915206
  • Gene:67956
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)