ZFIN ID: ZDB-GENE-060825-297
Gene Name: coenzyme Q6 monooxygenase
Gene Symbol: coq6    Nomenclature History

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Previous Name: zgc:153379

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have oxidoreductase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 6. Orthologous to human COQ6 (coenzyme Q6, monooxygenase).
Genome Resources: Alliance (1),  Gene:751691 (1),  Ensembl(GRCz11):ENSDARG00000060380 (2)
GENE EXPRESSION
All Expression Data: Fig. S1 from Heeringa et al., 2011
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45620 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-coq6 N/A 1
    MO2-coq6 N/A 1
    PHENOTYPE
    Data: Fig. 5 from Heeringa et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH coq6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    primary coenzyme Q10 deficiency 6 Alliance Coenzyme Q10 deficiency, primary, 6 614650
    DISEASE ASSOCIATED WITH coq6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cell projection (more)
    Molecular Function FAD binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA coq6-201 (1)    Ensembl 1906
    ncRNA coq6-002 (1)    Ensembl 382
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM coq6 No data available
    MARKER RELATIONSHIPS
    coq6 Contained in: [BAC] CH211-202H12 (1)
    coq6 Encodes: [cDNA] MGC:153379 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045404 (1) 1785 nt
    Genomic GenBank:BX936443 (1) 119991 nt
    Select Tool
    Polypeptide UniProtKB:F1RAX8 (1) 484 aa
    Sequence Information (all 14)
    ORTHOLOGY for coq6 ( Chr: 17 )
    CITATIONS (24)