Gene

serpinf2a

ID
ZDB-GENE-060822-1
Name
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
Symbol
serpinf2a Nomenclature History
Previous Names
  • serpinf2
  • serpinf2l (1)
  • wu:fd57d08
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Cheng et al., 2006
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With serpinf2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
alpha-2-plasmin inhibitor deficiency Alliance Alpha-2-plasmin inhibitor deficiency 262850
Associated With serpinf2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023796 Serpin domain
Family IPR000215 Serpin family
Homologous_superfamily IPR036186 Serpin superfamily
Homologous_superfamily IPR042178 Serpin superfamily, domain 1
Homologous_superfamily IPR042185 Serpin superfamily, domain 2
Domain Details Per Protein
Protein Length Serpin domain Serpin family Serpin superfamily Serpin superfamily, domain 1 Serpin superfamily, domain 2
UniProtKB:F6NQ58 457
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations