ZFIN ID: ZDB-GENE-060810-77
Gene Name: zgc:163030
Gene Symbol: zgc:163030    Nomenclature History

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Previous Name: im:7157354

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase inhibitor activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in CST3-related cerebral amyloid angiopathy and age related macular degeneration 11. Orthologous to several human genes including CST3 (cystatin C); CST5 (cystatin D); and CST4 (cystatin S).
Genome Resources: Alliance (1),  Gene:566959 (1),  Ensembl(GRCz11):ENSDARG00000069192 (2)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7157354]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42245 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zgc:163030 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zgc:163030 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component extracellular space (more)
    Molecular Function cysteine-type endopeptidase inhibitor activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zgc:163030-201 (1)    Ensembl 739
    zgc:163030-202 (1)    Ensembl 826
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zgc:163030 No data available
    MARKER RELATIONSHIPS
    zgc:163030 Contained in: [BAC] DKEY-76K16 (1) (order this)
    zgc:163030 Encodes: [EST] IMAGE:7157354 (1)
    [cDNA] MGC:163030 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089413 (1) 805 nt
    Genomic GenBank:BX005372 (1) 199736 nt
    Select Tool
    Polypeptide UniProtKB:A3KP81 (1) 128 aa
    Sequence Information (all 13)
    ORTHOLOGY for zgc:163030 ( Chr: 13 )
    CITATIONS (17)