ZFIN ID: ZDB-GENE-060810-52
Gene Name: SH3 and PX domains 2B
Gene Symbol: sh3pxd2b    Nomenclature History

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Previous Names: im:7155315, wu:fb09f08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol phosphate binding activity and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in superoxide metabolic process. Predicted to localize to cytoplasm. Is expressed in several structures, including central nervous system; notochord; otic vesicle; segmental plate; and tail bud. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B).
Genome Resources: Alliance (1),  Gene:553242 (1),  Ensembl(GRCz11):ENSDARG00000103251 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sh3pxd2b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Frank-Ter Haar syndrome Alliance Frank-ter Haar syndrome 249420
DISEASE ASSOCIATED WITH sh3pxd2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process bone development (more)
Cellular Component cytoplasm (more)
Molecular Function phosphatidylinositol binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sh3pxd2b-202 (1)    Ensembl 2833
sh3pxd2b-203 (1)    Ensembl 4561
ncRNA sh3pxd2b-002 (1)    Ensembl 535
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sh3pxd2b No data available
MARKER RELATIONSHIPS
sh3pxd2b Contained in: [Fosmid] CH1073-204B8 (1), CH1073-389N3 (1)
sh3pxd2b Encodes: [EST] fb09f08, IMAGE:7155315 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_005170288 (1) 4610 nt
Genomic GenBank:CU914161 (1) 38678 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IMX7 (1) 880 aa
Sequence Information (all 24)
ORTHOLOGY for sh3pxd2b ( Chr: 21 )
CITATIONS (17)