ZFIN ID: ZDB-GENE-060810-49
Gene Name: polypyrimidine tract binding protein 2b
Gene Symbol: ptbp2b    Nomenclature History

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Previous Names: ptbp2, im:7153495, si:ch211-160l17.2, wu:fa08f05, wu:fc05d10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in mRNA processing. Predicted to localize to the nucleus. Is expressed in central nervous system; cranial ganglion; retinal ganglion cell layer; and retinal inner nuclear layer. Orthologous to human PTBP2 (polypyrimidine tract binding protein 2).
Genome Resources: Alliance (1),  Gene:562434 (1),  Ensembl(GRCz11):ENSDARG00000015901 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [IMAGE:7153495]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ptbp2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ptbp2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process mRNA processing (more)
Cellular Component nucleus (more)
Molecular Function nucleic acid binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Family IPR006536 HnRNP-L/PTB
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Domain IPR021790 PTBP1, RNA recognition motif 2-like
Domain IPR034798 Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2
Domain IPR034799 PTBP2, RNA recognition motif 3
Domain IPR035002 PTBP2, RNA recognition motif 1
Homologous_superfamily IPR035979 RNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
aberrant processed transcript ptbp2b-203 (1)    Ensembl 759
mRNA ptbp2b-201 (1)    Ensembl 2900
ptbp2b-204 (1)    Ensembl 281
ncRNA ptbp2b-003 (1) 518
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ptbp2b No data available
MARKER RELATIONSHIPS
ptbp2b Contained in: [BAC] CH211-160L17 (1)
ptbp2b Encodes: [EST] fa08f05, fc05d10, IMAGE:7153495 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001100007 (1) 2826 bp
Genomic GenBank:BX005269 (1) 185170 bp
Select Tool
Polypeptide UniProtKB:A5PM68 (1) 538 aa
Sequence Information (all 21)
ORTHOLOGY for ptbp2b ( Chr: 2 )
CITATIONS (21)