Gene

lratb.1

ID
ZDB-GENE-060810-31
Name
lecithin retinol acyltransferase b, tandem duplicate 1
Symbol
lratb.1 Nomenclature History
Previous Names
  • lratb
  • im:7148552
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Exhibits phosphatidylcholine-retinol O-acyltransferase activity. Involved in retinol metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Is expressed in several structures, including central nervous system; hindbrain neural keel; margin; mesoderm; and neural crest. Orthologous to human LRAT (lecithin retinol acyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Isken et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lratb.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leber congenital amaurosis 14 Alliance Leber congenital amaurosis 14 613341
Leber congenital amaurosis 14 Alliance Retinal dystrophy, early-onset severe 613341
Leber congenital amaurosis 14 Alliance Retinitis pigmentosa, juvenile 613341
Associated With lratb.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007053 LRAT domain
Family IPR042288 Lecithin retinol acyltransferase
Domain Details Per Protein
Protein Length Lecithin retinol acyltransferase LRAT domain
UniProtKB:F6PF49 231
UniProtKB:Q5EAQ3 231
UniProtKB:A0A2R8PZT4 226
UniProtKB:A4VAJ7 121
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations