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ZIRC
ZFIN ID: ZDB-GENE-060810-148
Gene Name: WD repeat domain 35
Gene Symbol: wdr35    Nomenclature History

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Previous Names: im:7159945 (1), si:ch211-206k20.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Involved in cilium assembly. Predicted to localize to the axoneme and intraciliary transport particle A. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; Sensenbrenner syndrome; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35).
Genome Resources: Alliance (1),  Gene:565515 (1),  Ensembl(GRCz11):ENSDARG00000069269 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7159945]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
DISEASE ASSOCIATED WITH wdr35 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sensenbrenner syndrome Alliance Cranioectodermal dysplasia 2 613610
short-rib thoracic dysplasia 7 with or without polydactyly Alliance Short-rib thoracic dysplasia 7 with or without polydactyly 614091
DISEASE ASSOCIATED WITH wdr35 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cilium assembly (more)
Cellular Component cell projection (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (nt) Analysis
aberrant processed transcript wdr35-203 (1)    Ensembl 800
mRNA wdr35-201 (1)    Ensembl 4088
ncRNA wdr35-003 (1)    Ensembl 584
wdr35-004 (1)    Ensembl 865
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM wdr35 No data available
MARKER RELATIONSHIPS
wdr35 Contained in: [BAC] CH211-206K20 (1) (order this)
wdr35 Encodes: [EST] IMAGE:7159945 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001145589 (1)
Genomic GenBank:AL935163 (1) 158350 bp
Select Tool
Polypeptide UniProtKB:B7ZD88 (1) 1203 aa
Sequence Clusters UniGene:87936 (1)
Sequence Information (all 10)
ORTHOLOGY for wdr35 ( Chr: 13 )
CITATIONS (20)