ZFIN ID: ZDB-GENE-060810-116
Gene Name: polymerase (DNA directed), gamma 2, accessory subunit
Gene Symbol: polg2    Nomenclature History

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Attributions

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Previous Names: im:7158733 (1), si:ch211-157f15.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to be involved in mitochondrial DNA replication. Predicted to localize to mitochondrion. Is expressed in retina. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 and mitochondrial DNA depletion syndrome. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit).
Genome Resources: Alliance (1),  Gene:100150674 (1),  Ensembl(GRCz11):ENSDARG00000074933 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7158733]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH polg2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 Alliance Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 4 610131
Mitochondrial DNA depletion syndrome 16 (hepatic type) 618528
DISEASE ASSOCIATED WITH polg2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process DNA repair (more)
Cellular Component mitochondrion (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA polg2-001 (1) 1816
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM polg2 No data available
MARKER RELATIONSHIPS
polg2 Contained in: [BAC] CH211-157F15 (1)
polg2 Encodes: [EST] IMAGE:7158733 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_001922324 (1)
Genomic GenBank:CR450715 (1) 137471 nt
Select Tool
Polypeptide UniProtKB:E7F4P9 (1) 442 aa
Sequence Information (all 8)
ORTHOLOGY for polg2 ( Chr: 6 )
CITATIONS (20)