ZFIN ID: ZDB-GENE-070627-13
Gene Name: mediator complex subunit 13a
Gene Symbol: med13a    Nomenclature History

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Previous Names: med13 (1), im:7158513 (1), si:dkeyp-53h3.2, thrap1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to the mediator complex. Orthologous to human MED13 (mediator complex subunit 13).
Genome Resources: Alliance (1),  Gene:100004024 (1),  Ensembl(GRCz11):ENSDARG00000053884 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7158513]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017492Tg Transgenic Insertion Unknown Unknown DNA
la027164Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1643 Point Mutation Unknown Splice Site ENU
    sa13843 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16900 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21755 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41677 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45410 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-med13a N/A 2
    MO2-med13a N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH med13a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Intellectual developmental disorder 61 618009
    DISEASE ASSOCIATED WITH med13a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component mediator complex (more)
    Molecular Function transcription coregulator activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR009401 Mediator complex subunit Med13, C-terminal
    Domain IPR021643 Mediator complex, subunit Med13, N-terminal, metazoa/fungi
    Domain IPR041285 MID domain of medPIWI
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA med13a-202 (1)    Ensembl 8107
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM med13a No data available
    MARKER RELATIONSHIPS
    med13a Contained in: [BAC] CH211-266O3 (1), DKEY-149M16 (1) (order this), DKEYP-53H3 (1)
    med13a Encodes: [EST] IMAGE:7158513 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001281468 (1) 7513 bp
    Genomic GenBank:BX664626 (1) 200968 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QD69 (1) 2197 aa
    Sequence Information (all 15)
    ORTHOLOGY for med13a ( Chr: 10 )
    CITATIONS (23)