ZFIN ID: ZDB-GENE-060810-103
Gene Name: si:dkey-38p12.3
Gene Symbol: si:dkey-38p12.3    Nomenclature History

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Previous Name: im:7158374 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity. Orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15).
Genome Resources: Alliance (1),  Gene:555489 (1),  Ensembl(GRCz11):ENSDARG00000061844 (2)

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7158374]
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6251 Point Mutation Unknown Premature Stop ENU
sa22088 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35285 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH si:dkey-38p12.3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH si:dkey-38p12.3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process activation of GTPase activity (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:dkey-38p12.3-201 (1)    Ensembl 4238
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM si:dkey-38p12.3 No data available
    MARKER RELATIONSHIPS
    si:dkey-38p12.3 Contained in: [BAC] DKEY-38P12 (1) (order this)
    si:dkey-38p12.3 Encodes: [EST] IMAGE:7158374 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_678013 (1) 3277 nt
    Genomic GenBank:AL929346 (1) 232537 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F1T2 (1) 937 aa
    Sequence Information (all 18)
    ORTHOLOGY for si:dkey-38p12.3 ( Chr: 12 )
    CITATIONS (14)