ZFIN Gene: rerea

ZFIN ID: ZDB-GENE-060718-1

ZFIN ID: ZDB-GENE-060718-1

Gene Name:

arginine-glutamic acid dipeptide (RE) repeats a

Gene Symbol:

rerea Nomenclature History

Previous Names:

rere, rereb, atrophin 2 (1), atrophin2 (1), bab (1), babyface (1), gap (1), gaping mouth (1)

Gene Type:

protein_coding_gene

Location:

Chr: 23 Mapping Details/Browsers

Description:

Predicted to have DNA binding activity; RNA polymerase II transcription factor binding activity; and transcription corepressor activity. Involved in several processes, including pharyngeal system development; regulation of histone deacetylation; and regulation of signal transduction. Predicted to localize to nucleus. Is expressed in several structures, including germ ring; gut; head; nervous system; and pectoral fin bud. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats).

Genome Resources:

Alliance (1), Gene:569081 (1), Ensembl(GRCz11):ENSDARG00000077353 (2)

GENE EXPRESSION
All Expression Data:	4 figures from 3 publications
Wild-type Stages, Structures:	Blastula:Sphere (4.0h-4.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
	brain central nervous system germ ring gut head intestine pectoral fin pectoral fin bud pharyngeal arch retina shield somite spinal cord whole organism
High Throughput Expression:	Expression Atlas (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la022560Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la028506Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la028507Tg	Transgenic Insertion	Unknown	Unknown	DNA
la028508Tg	Transgenic Insertion	Unknown	Unknown	DNA
ru622	Point Mutation	Donor Splice Site of Intron 12	Premature Stop	ENU
sa1112	Point Mutation	Unknown	Premature Stop	ENU
sa8509	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa9631	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa10433	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa13495	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa24320	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa24321	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa32440	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
tb210	Unknown	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
tw220c	Unknown	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
CRISPR1-rerea		2
CRISPR2-rerea		2
CRISPR3-rerea		2
CRISPR4-rerea		2
CRISPR5-rerea		2
CRISPR6-rerea		2
CRISPR7-rerea		2
CRISPR8-rerea		2
CRISPR9-rerea		2
MO1-rerea	N/A	3

PHENOTYPE

Data:

16 figures from 5 publications

Observed in:

DISEASE ASSOCIATED WITH rerea HUMAN ORTHOLOG

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart	616975

DISEASE ASSOCIATED WITH rerea VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	pharyngeal system development (more)
Cellular Component	nucleus (more)
Molecular Function	chromatin binding (more)

GO Terms (all 15)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	rerea-202 (1)	4173	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	rerea-203 (1)	720	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM rerea No data available

MARKER RELATIONSHIPS

rerea Contained in:

[BAC] CH211-273O6 (1), DKEY-24D19 (1) (order this), DKEY-216D12 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_005162201 (1)	7733 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	RefSeq:NW_018395147 (1)		Blast at MegaBLAST
Polypeptide	UniProtKB:E7F226 (1)	1531 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 38)

ORTHOLOGY for rerea ( Chr: 23 )

CITATIONS (36)

{{control.fieldName}} Edit

Attributions

Add new Alias

Attributions for Alias: {{control.newAlias}}

Delete Alias: