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ZIRC
ZFIN ID: ZDB-GENE-060718-1
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Gene Name: arginine-glutamic acid dipeptide (RE) repeats a
Gene Symbol: rerea    Nomenclature History

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Previous Names: rere, rereb, atrophin 2 (1), atrophin2 (1), bab (1), babyface (1), gap (1), gaping mouth (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; RNA polymerase II transcription factor binding activity; and transcription corepressor activity. Involved in several processes, including pharyngeal system development; regulation of histone deacetylation; and regulation of signal transduction. Predicted to localize to the nucleus. Is expressed in several structures, including germ ring; gut; head; nervous system; and pectoral fin bud. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats).
Genome Resources: Alliance (1),  Gene:569081 (1),  Ensembl(GRCz11):ENSDARG00000077353 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022560Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la028506Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la028507Tg Transgenic Insertion Unknown Unknown DNA
    la028508Tg Transgenic Insertion Unknown Unknown DNA
    ru622 Point Mutation Donor Splice Site of Intron 12 Premature Stop ENU
    sa1112 Point Mutation Unknown Premature Stop ENU
    sa8509 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa9631 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa10433 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa13495 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24320 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24321 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa32440 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • tb210 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • tw220c Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rerea
    		2
    CRISPR2-rerea
    		2
    CRISPR3-rerea
    		2
    CRISPR4-rerea
    		2
    CRISPR5-rerea
    		2
    CRISPR6-rerea
    		2
    CRISPR7-rerea
    		2
    CRISPR8-rerea
    		2
    CRISPR9-rerea
    		2
    MO1-rerea N/A 3
    PHENOTYPE
    Data: 16 figures from 5 publications
    Observed in:
    DISEASE ASSOCIATED WITH rerea HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart 616975
    DISEASE ASSOCIATED WITH rerea VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pharyngeal system development (more)
    Cellular Component nucleus (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000679 (1)
  • InterPro:IPR000949 (1)
  • InterPro:IPR001005 (1)
  • InterPro:IPR001025 (1)
  • InterPro:IPR002951 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017884 (1)
  • InterPro:IPR017993 (1)
  • PROSITE:PS51038 (1)
  • PROSITE:PS51156 (1)
  • PROSITE:PS51293 (1)
  • Pfam:PF00320 (1)
  • Pfam:PF01426 (1)
  • Pfam:PF01448 (1)
  • Pfam:PF03154 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rerea-202 (1)    Ensembl 4173
    Select Tool
    rerea-203 (1)    Ensembl 720
    Select Tool
    Browsers: NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rerea No data available
    MARKER RELATIONSHIPS
    rerea Contained in: [BAC] CH211-273O6 (1) (order this), DKEY-24D19 (1) (order this), DKEY-216D12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005162201 (1) 7733 bp
    Select Tool
    Genomic RefSeq:NW_018395147 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:E7F226 (1) 1531 aa
    Select Tool
    Sequence Clusters UniGene:84771 (1)
    Sequence Information (all 40)
    ORTHOLOGY for rerea ( Chr: 23 )
    CITATIONS (35)