Gene

scube3

ID
ZDB-GENE-060717-1
Name
signal peptide, CUB domain, EGF-like 3
Symbol
scube3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in skeletal muscle fiber development and smoothened signaling pathway. Predicted to localize to cell surface and extracellular space. Is expressed in several structures, including blastomere; central nervous system; optic cup; segmental plate; and solid lens vesicle. Orthologous to human SCUBE3 (signal peptide, CUB domain and EGF like domain containing 3).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With scube3 Human Ortholog
No data available
Associated With scube3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR013032 EGF-like, conserved site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR000859 CUB domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
Domain IPR024731 EGF domain
Domain IPR026823 Complement Clr-like EGF domain
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Complement Clr-like EGF domain CUB domain EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like, conserved site EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Spermadhesin, CUB domain superfamily Tyrosine-protein kinase ephrin type A/B receptor-like
UniProtKB:A0A2R8Q191 1002
UniProtKB:F1R0I7 995
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations