ZFIN ID: ZDB-GENE-060711-1
Gene Name: fibulin 2
Gene Symbol: fbln2    Nomenclature History

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Previous Name: im:6907068

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Predicted to be involved in extracellular matrix organization. Predicted to localize to the collagen-containing extracellular matrix. Is expressed in several structures, including cardiovascular system; hypochord; intestinal bulb; mesoderm; and tail bud. Orthologous to human FBLN2 (fibulin 2).
Genome Resources: Alliance (1),  Gene:553503 (1),  Ensembl(GRCz11):ENSDARG00000015156 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa812 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1922 Point Mutation Unknown Premature Stop ENU
    sa8965 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15910 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16218 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21928 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21929 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35098 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41852 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41853 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fbln2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fbln2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process extracellular matrix organization (more)
    Cellular Component collagen-containing extracellular matrix (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000020 Anaphylatoxin/fibulin
    PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
    Domain IPR000742 EGF-like domain
    Domain IPR001881 EGF-like calcium-binding domain
    Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
    Conserved_site IPR013032 EGF-like, conserved site
    Conserved_site IPR018097 EGF-like calcium-binding, conserved site
    Domain IPR026823 Complement Clr-like EGF domain
    Family IPR037286 Fibulin-2
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fbln2-201 (1)    Ensembl 5443
    fbln2-203 (1)    Ensembl 661
    fbln2-204 (1)    Ensembl 912
    ncRNA fbln2-003 (1)    Ensembl 504
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fbln2 No data available
    MARKER RELATIONSHIPS
    fbln2 Contained in: [BAC] DKEY-23P14 (1) (order this)
    fbln2 Encodes: [EST] IMAGE:6907068 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001341241 (1) 5414 bp
    Genomic GenBank:CR555293 (1) 280078 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1RCR3 (1) 1408 aa
    Sequence Information (all 21)
    ORTHOLOGY for fbln2 ( Chr: 11 )
    CITATIONS (18)