ZFIN ID: ZDB-GENE-060628-1
Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Gene Symbol: tab1    Nomenclature History

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Previous Names: Tab1 (1), map3k7ip1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity; mitogen-activated protein kinase p38 binding activity; and protein kinase activator activity. Involved in neutrophil chemotaxis. Predicted to localize to the cytosol and nucleus. Orthologous to human TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1).
Genome Resources: Alliance (1),  Gene:403084 (1),  Ensembl(GRCz11):ENSDARG00000036613 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tab1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tab1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neutrophil chemotaxis (more)
Cellular Component cytosol (more)
Molecular Function catalytic activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001932 PPM-type phosphatase domain
Family IPR015655 Protein phosphatase 2C family
Homologous_superfamily IPR036457 PPM-type phosphatase domain superfamily
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tab1 No data available
MARKER RELATIONSHIPS No data available
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_002662240 (1)
Genomic GenBank:CABZ01084567 (1) 8808 bp
Polypeptide UniProtKB:Q6NUU7 (1) 498 aa
Sequence Information (all 11)
ORTHOLOGY for tab1 ( Chr: 6 )
CITATIONS (18)