Gene
plcb4b
- ID
- ZDB-GENE-060627-1
- Name
- phospholipase C, beta 4b
- Symbol
- plcb4b Nomenclature History
- Previous Names
-
- plcb4
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Predicted to be located in plasma membrane. Is expressed in spinal cord. Orthologous to human PLCB4 (phospholipase C beta 4).
- Genome Resources
-
- Alliance (1)
- Gene:407700 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain |
| Domain | IPR014815 | Phospholipase C-beta, C-terminal domain |
| Domain | IPR037862 | PLC-beta, PH domain |
| Domain | IPR053945 | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Family | IPR016280 | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR042531 | Phospholipase C-beta, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | EF-hand domain pair | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain | Phosphoinositide phospholipase C family | Phospholipase C-beta, C-terminal domain | Phospholipase C-beta, C-terminal domain superfamily | Phospholipase C, phosphatidylinositol-specific, Y domain | PLC-beta, PH domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TKB8 | InterPro | 1343 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance