ZFIN ID: ZDB-GENE-060616-382
Gene Name: integrin, alpha V
Gene Symbol: itgav    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:136222 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Involved in several processes, including Kupffer's vesicle development; axis elongation involved in somitogenesis; and endothelial cell proliferation. Localizes to integrin complex. Is expressed in several structures, including axis; diencephalon; head; pleuroperitoneal region; and post-vent vasculature. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and acute myeloid leukemia. Orthologous to human ITGAV (integrin subunit alpha V).
Genome Resources: Alliance (1),  Gene:100151255 (1),  Ensembl(GRCz11):ENSDARG00000006314 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016467Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31703 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34569 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41365 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-itgav N/A 3
    MO2-itgav N/A 1
    MO3-itgav N/A 1
    MO4-itgav N/A 1
    MO5-itgav N/A 3
    DISEASE ASSOCIATED WITH itgav HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH itgav VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integrin complex (more)
    Molecular Function protein binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA itgav-201 (1)    Ensembl 4328
    ncRNA itgav-002 (1)    Ensembl 1338
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM itgav No data available
    MARKER RELATIONSHIPS
    itgav Contained in: [BAC] DKEY-69O16 (1) (order this)
    itgav Encodes: [cDNA] MGC:136222 (1), MGC:195124 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001033721 (1) 4301 nt
    Genomic GenBank:CU468956 (1) 156034 nt
    Select Tool
    Polypeptide UniProtKB:B3DJQ3 (1) 1045 aa
    Sequence Information (all 20)
    ORTHOLOGY for itgav ( Chr: 9 )
    CITATIONS (41)