ZFIN Gene: adgrb1a

ZFIN ID: ZDB-GENE-060607-12

ZFIN ID: ZDB-GENE-060607-12

Gene Name:

adhesion G protein-coupled receptor B1a

Gene Symbol:

adgrb1a Nomenclature History

Previous Names:

bai1a, si:ch211-80e15.1 (1), wu:fq36h12 (1), zmp:0000000766

Gene Type:

protein_coding_gene

Location:

Chr: 16 Mapping Details/Browsers

Description:

Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and engulfment of apoptotic cell. Predicted to localize to several cellular components, including dendrite; glutamatergic synapse; and postsynaptic density. Is expressed in muscle; nervous system; and testis. Human ortholog(s) of this gene implicated in glioblastoma multiforme. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1).

Genome Resources:

Alliance (1), Gene:563527 (1), Ensembl(GRCz11):ENSDARG00000075133 (2)

GENE EXPRESSION
All Expression Data:	13 figures from 2 publications
Directly Submitted Expression Data:	12 figures (31 images) from Rauch et al., 2003 [fq36h12]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
	brain central nervous system eye lateral line muscle neuron peripheral nervous system retina sensory neuron spinal cord testis unspecified whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa12101	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa14551	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa15683	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa22905	Point Mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa22909	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa32102	Point Mutation	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa36209	Point Mutation	Unknown	Unknown	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa42780	Point Mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa42781	Point Mutation	Unknown	Unknown	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa42782	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa44857	Point Mutation	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
CRISPR1-adgrb1a		1

PHENOTYPE No data available

DISEASE ASSOCIATED WITH adgrb1a HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH adgrb1a VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cell surface receptor signaling pathway (more)
Cellular Component	integral component of membrane (more)
Molecular Function	G protein-coupled receptor activity (more)

GO Terms (all 14)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	adgrb1a-203 (1)	3497	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	adgrb1a-002 (1)	1391	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM adgrb1a No data available

MARKER RELATIONSHIPS

adgrb1a Contained in:	[BAC] CH211-80E15 (1), CH211-236O11 (1)
adgrb1a Encodes:	[EST] fq36h12 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_009292551 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:AL953880 (1)	161603 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A2R8PX08 (1)	1610 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 42)

ORTHOLOGY for adgrb1a ( Chr: 16 )

CITATIONS (23)

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