Gene

npr3

ID
ZDB-GENE-060531-91
Name
natriuretic peptide receptor 3
Symbol
npr3 Nomenclature History
Previous Names
  • im:7138418
  • si:dkey-199l1.2 (1)
  • zgc:158440
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Acts upstream of or within cardiac muscle cell proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including heart; hypochord; nervous system; neural tube; and renal system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Becker et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With npr3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Hypertension, salt-resistant
Associated With npr3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001828 Receptor, ligand binding region
Family IPR001170 Adenylyl cyclase class-4/guanylyl cyclase
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Domain Details Per Protein
Protein Length Adenylyl cyclase class-4/guanylyl cyclase Periplasmic binding protein-like I Receptor, ligand binding region
UniProtKB:A0A2R8QSY4 488
UniProtKB:F1R7C4 502
UniProtKB:A0A2R8RSJ1 503
UniProtKB:A2RUY7 472
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations