ZFIN ID: ZDB-GENE-060531-67
Gene Name: F11 receptor, tandem duplicate 2
Gene Symbol: f11r.2    Nomenclature History

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Previous Names: f11rl, jam1b (1), jama2 (1), si:ch211-89p1.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to be involved in establishment of endothelial intestinal barrier; intestinal absorption; and regulation of membrane permeability. Predicted to localize to the bicellular tight junction. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including immature eye; integument; otic vesicle; pronephric duct; and sensory system. Orthologous to human F11R (F11 receptor).
Genome Resources: Alliance (1),  Gene:100005566 (1),  Ensembl(GRCz11):ENSDARG00000068114 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38 Point Mutation Unknown Unknown ENU
sa26496 Point Mutation Unknown Splice Site ENU
sa26497 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH f11r.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH f11r.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component bicellular tight junction (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Family IPR042456 Junctional adhesion molecule A
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA f11r.2-202 (1)    Ensembl 847
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM f11r.2 No data available
MARKER RELATIONSHIPS
f11r.2 Contained in: [BAC] CH73-99I6 (1), CH211-89P1 (1)
f11r.2 Encodes: [cDNA] MGC:162181 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001082982 (1) 1453 nt
Genomic GenBank:CT027580 (1) 33220 nt
Select Tool
Polypeptide UniProtKB:A3KNL2 (1) 294 aa
Sequence Information (all 18)
ORTHOLOGY for f11r.2 ( Chr: 5 )
CITATIONS (19)