ZFIN ID: ZDB-GENE-060531-50
Gene Name: myosin, heavy chain a
Gene Symbol: myha    Nomenclature History

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Previous Names: fmyhc2.3 (1), si:ch211-251m3.3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to the myosin complex. Human ortholog(s) of this gene implicated in disease of cellular proliferation; distal arthrogryposis; inclusion body myositis; and multiple pterygium syndrome. Is expressed in caudal fin; cephalic musculature; muscle; and trunk. Orthologous to several human genes including MYH1 (myosin heavy chain 1).
Genome Resources: Alliance (1),  Gene:100149148 (1),  Ensembl(GRCz11):ENSDARG00000095930 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myha HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH myha VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myosin complex (more)
Molecular Function actin binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR002928 Myosin tail
Domain IPR004009 Myosin, N-terminal, SH3-like
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR027401 Myosin IQ motif-containing domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myha-201 (1)    Ensembl 5915
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myha No data available
MARKER RELATIONSHIPS
myha Contained in: [BAC] CH211-158M24 (1), CH211-251M3 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_021476518 (1)
Genomic GenBank:BX510649 (1) 189844 bp
Select Tool
Polypeptide UniProtKB:F1R6C7 (1) 1933 aa
Sequence Information (all 7)
ORTHOLOGY for myha ( Chr: 5 )
CITATIONS (23)