Gene

cacna1ba

ID
ZDB-GENE-060531-44
Name
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
Symbol
cacna1ba Nomenclature History
Previous Names
  • cacna1b (1)
  • CACNA1Bb (1)
  • si:ch211-238e12.1 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have voltage-gated calcium channel activity. Predicted to be involved in calcium ion import and chemical synaptic transmission. Predicted to localize to voltage-gated calcium channel complex. Is expressed in atrium; brain; cardiac ventricle; and liver. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome and dystonia 23. Orthologous to human CACNA1B (calcium voltage-gated channel subunit alpha1 B).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cacna1ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements 618497
Associated With cacna1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
Domain IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domain
Family IPR002077 Voltage-dependent calcium channel, alpha-1 subunit
Family IPR005447 Voltage-dependent calcium channel, N-type, alpha-1 subunit
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain Voltage-dependent calcium channel, alpha-1 subunit Voltage-dependent calcium channel, alpha-1 subunit, IQ domain Voltage-dependent calcium channel, N-type, alpha-1 subunit Voltage-dependent channel domain superfamily Voltage-dependent L-type calcium channel, IQ-associated domain
UniProtKB:T2B1R0 2194
UniProtKB:A2BHF3 2270
UniProtKB:A2BHF4 2312
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations