ZFIN ID: ZDB-GENE-060531-28
Gene Name: Rho guanine nucleotide exchange factor (GEF) 28a
Gene Symbol: arhgef28a    Nomenclature History

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Previous Names: arhgef28 (1), rgnef (1), p190RhoGEF (1), si:ch211-1o14.5 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in Golgi organization; cell-matrix adhesion; and muscle tissue morphogenesis. Is expressed in ball; head; notochord; somite; and trunk. Orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28).
Genome Resources: Alliance (1),  Gene:559941 (1),  Ensembl(GRCz11):ENSDARG00000060415 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029085Tg Transgenic Insertion Unknown Unknown DNA
sa16048 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20469 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26517 Point Mutation Unknown Premature Stop ENU
    sa26519 Point Mutation Unknown Premature Stop ENU
    sa40485 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40486 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arhgef28a N/A 1
    DISEASE ASSOCIATED WITH arhgef28a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arhgef28a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle tissue morphogenesis (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arhgef28-202 (1)    Ensembl 6200
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef28a No data available
    MARKER RELATIONSHIPS
    arhgef28a Contained in: [BAC] CH211-1O14 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009301598 (1)
    Genomic RefSeq:NW_018394590 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:F6P6M2 (1) 1753 aa
    Sequence Information (all 38)
    ORTHOLOGY for arhgef28a ( Chr: 5 )
    CITATIONS (23)