ZFIN ID: ZDB-GENE-060531-160
Gene Name: N-ethylmaleimide-sensitive factor attachment protein, alpha a
Gene Symbol: napaa    Nomenclature History

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Previous Names: alpha-snap2 (1), si:dkeyp-117b8.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have soluble NSF attachment protein activity and syntaxin binding activity. Predicted to be involved in several processes, including SNARE complex disassembly; glutamatergic synaptic transmission; and regulation of synaptic vesicle priming. Predicted to localize to synaptobrevin 2-SNAP-25-syntaxin-1a complex and vacuolar membrane. Is expressed in head. Orthologous to human NAPA (NSF attachment protein alpha).
Genome Resources: Alliance (1),  Gene:567306 (1),  Ensembl(GRCz11):ENSDARG00000067605 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from Nishiwaki et al., 2013
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Hatching:Pec-fin (60.0h-72.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH napaa HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH napaa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular protein transport (more)
Cellular Component SNARE complex (more)
Molecular Function soluble NSF attachment protein activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA napaa-201 (1)    Ensembl 2511
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM napaa No data available
MARKER RELATIONSHIPS
napaa Contained in: [BAC] DKEYP-117B8 (1)
napaa Encodes: [cDNA] MGC:162296 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001083561 (1) 1157 nt
Genomic GenBank:CR759879 (1) 110254 nt
Select Tool
Polypeptide UniProtKB:A2CET2 (1) 295 aa
Sequence Information (all 10)
ORTHOLOGY for napaa ( Chr: 5 )
CITATIONS (18)