ZFIN ID: ZDB-GENE-060531-130
Gene Name: proprotein convertase subtilisin/kexin type 5a
Gene Symbol: pcsk5a    Nomenclature History

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Previous Names: pc5.1 (1), pcsk5.1 (1), PCSK5/6a, si:dkey-267i17.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase activity. Involved in anterior lateral line development and neuromast development. Predicted to localize to integral component of Golgi membrane and trans-Golgi network. Is expressed in several structures, including eye; lateral line system; liver; otic vesicle; and pleuroperitoneal region. Orthologous to human PCSK5 (proprotein convertase subtilisin/kexin type 5).
Genome Resources: Alliance (1),  Gene:571235 (1),  Ensembl(GRCz11):ENSDARG00000067537 (2)
DISEASE ASSOCIATED WITH pcsk5a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pcsk5a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior lateral line development (more)
Cellular Component integral component of membrane (more)
Molecular Function hydrolase activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pcsk5a-201 (1)    Ensembl 5466
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pcsk5a No data available
MARKER RELATIONSHIPS
pcsk5a Contained in: [BAC] DKEY-267I17 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001077582 (1) 3495 nt
Genomic GenBank:BX571945 (1) 192769 nt
Select Tool
Polypeptide UniProtKB:A2BHH6 (1) 1821 aa
Sequence Information (all 12)
ORTHOLOGY for pcsk5a ( Chr: 5 )
CITATIONS (27)