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ZIRC
ZFIN ID: ZDB-GENE-060526-71
Gene Name: pregnancy-associated plasma protein A, pappalysin 1b
Gene Symbol: pappab    Nomenclature History

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Previous Name: si:ch211-196f15.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits peptidase activity. Involved in chordate embryonic development. Human ortholog(s) of this gene implicated in myocardial infarction. Is expressed in several structures, including digestive system; muscle; nervous system; pleuroperitoneal region; and skeletal tissue. Orthologous to human PAPPA (pappalysin 1).
Genome Resources: Alliance (1),  Gene:101448001 (1),  Ensembl(GRCz11):ENSDARG00000059858 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9050 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12988 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13003 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20569 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20570 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25317 Point Mutation Unknown Premature Stop ENU
    sa33750 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44625 Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pappab N/A 1
    MO2-pappab N/A 1
    DISEASE ASSOCIATED WITH pappab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pappab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Molecular Function peptidase activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pappab-202 (1)    Ensembl 599
    pappab-203 (1)    Ensembl 4821
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pappab No data available
    MARKER RELATIONSHIPS
    pappab Contained in: [BAC] CH211-89C12 (order this), CH211-155E19 (order this), CH211-196F15 (1) (order this), DKEY-43F11 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001278808 (1) 5093 bp
    Genomic GenBank:AL845516 (1) 205826 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5Q4 (1) 1624 aa
    Sequence Information (all 16)
    ORTHOLOGY for pappab ( Chr: 5 )
    CITATIONS (12)