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Gene

htr7c

ID
ZDB-GENE-060526-5
Name
5-hydroxytryptamine (serotonin) receptor 7c
Symbol
htr7c Nomenclature History
Previous Names
  • si:ch211-10p21.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to act upstream of or within several processes, including circadian rhythm; smooth muscle contraction; and vasoconstriction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in alcohol use disorder. Orthologous to human HTR7 (5-hydroxytryptamine receptor 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Sourbron et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With htr7c Human Ortholog
No data available
Associated With htr7c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001069 5-Hydroxytryptamine 7 receptor
Family IPR002231 5-hydroxytryptamine receptor family
Domain Details Per Protein
Protein Length 5-Hydroxytryptamine 7 receptor 5-hydroxytryptamine receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:A2CEI8 112
UniProtKB:A0A0R4IHZ4 400
UniProtKB:F1R0N3 248
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations