ZFIN ID: ZDB-GENE-060526-377
Gene Name: whirlin b
Gene Symbol: whrnb    Nomenclature History

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Previous Names: dfnb31b (1), si:rp71-10d23.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to be involved in sensory perception of sound. Predicted to colocalize with the photoreceptor connecting cilium and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Usher syndrome type 2D; autosomal recessive nonsyndromic deafness 31; and sensorineural hearing loss. Is expressed in hair cell. Orthologous to human WHRN (whirlin).
Genome Resources: Alliance (1),  Gene:100534775 (1),  Ensembl(GRCz11):ENSDARG00000068166 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH whrnb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 31 Alliance Deafness, autosomal recessive 31 607084
Usher syndrome type 2D Alliance Usher syndrome, type 2D 611383
DISEASE ASSOCIATED WITH whrnb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sensory perception of light stimulus (more)
Cellular Component COLOCALIZES_WITH   photoreceptor connecting cilium (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001478 PDZ domain
Family IPR033028 Whirlin
Homologous_superfamily IPR036034 PDZ superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA whrnb-202 (1)    Ensembl 718
whrnb-203 (1)    Ensembl 7982
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM whrnb No data available
MARKER RELATIONSHIPS
whrnb Contained in: [BAC] CH73-244M7 (1), DKEY-61L1 (1) (order this), RP71-10D23 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_005171948 (1)
Genomic GenBank:BX470066 (1) 178499 bp
Select Tool
Polypeptide UniProtKB:F1R807 (1) 946 aa
Sequence Information (all 15)
ORTHOLOGY for whrnb ( Chr: 5 )
CITATIONS (16)