Gene

alkbh2

ID
ZDB-GENE-060526-327
Name
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Symbol
alkbh2 Nomenclature History
Previous Names
  • si:dkey-65b12.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA-N1-methyladenine dioxygenase activity; cytosine C-5 DNA demethylase activity; and ferrous iron binding activity. Predicted to be involved in DNA dealkylation involved in DNA repair and oxidative DNA demethylation. Orthologous to human ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alkbh2 Human Ortholog
No data available
Associated With alkbh2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005123 Oxoglutarate/iron-dependent dioxygenase
Domain IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like
Family IPR032852 DNA oxidative demethylase ALKBH2
Homologous_superfamily IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily
Domain Details Per Protein
Protein Length Alpha-ketoglutarate-dependent dioxygenase AlkB-like Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily DNA oxidative demethylase ALKBH2 Oxoglutarate/iron-dependent dioxygenase
UniProtKB:A3QK41 258
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA alkbh2-201 (1) Havana 999 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations