Gene

idua

ID
ZDB-GENE-060526-29
Name
alpha-L-iduronidase
Symbol
idua Nomenclature History
Previous Names
  • si:ch211-12e13.9 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have L-iduronidase activity. Predicted to be involved in carbohydrate metabolic process. Human ortholog(s) of this gene implicated in Scheie syndrome; mucopolysaccharidosis I; mucopolysaccharidosis Ih; and mucopolysaccharidosis Ih/s. Orthologous to human IDUA (alpha-L-iduronidase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With idua Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mucopolysaccharidosis Ih Alliance Mucopolysaccharidosis Ih 607014
mucopolysaccharidosis Ih/s Alliance Mucopolysaccharidosis Ih/s 607015
Scheie syndrome Alliance Mucopolysaccharidosis Is 607016
Associated With idua Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000514 Glycoside hydrolase, family 39
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR017853 Glycoside hydrolase superfamily
Domain Details Per Protein
Protein Length Glycoside hydrolase, family 39 Glycoside hydrolase superfamily Immunoglobulin-like fold
UniProtKB:A2ARH2 637
UniProtKB:A0A2R9YJN2 438
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations