Gene

alkbh4

ID

ZDB-GENE-060526-275

Name

alkB homolog 4, lysine demthylase

Symbol

alkbh4 Nomenclature History

Previous Names

si:dkey-261j4.10

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have actin binding activity; demethylase activity; and oxidoreductase activity. Involved in epiboly involved in gastrulation with mouth forming second and regulation of actomyosin structure organization. Predicted to localize to contractile ring and midbody. Is expressed in blastomere; forebrain; midbrain; oocyte; and otic vesicle. Orthologous to human ALKBH4 (alkB homolog 4, lysine demethylase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Sun et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Sun et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With alkbh4 Human Ortholog

No data available

Associated With alkbh4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR032857	Alpha-ketoglutarate-dependent dioxygenase alkB homologue 4
Homologous_superfamily	IPR037151	Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily