ZFIN ID: ZDB-GENE-060526-274
Gene Name: solute carrier family 4 member 4a
Gene Symbol: slc4a4a
Sequence Ontology ID : SO:0000704

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Previous Names: slc4a4, id:ibd2520, NBC1 (1), NBCe1 (1), si:dkey-256m11.1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sodium:bicarbonate symporter activity; predicted to be involved in bicarbonate transport and regulation of intracellular pH; predicted to localize to the integral component of plasma  ...
GENE EXPRESSION
All Expression Data: 23 figures from 16 publications
Directly Submitted Expression Data: 2 figures (4 images) from Kudoh et al., 2001 [ibd2520]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6999 Point Mutation Unknown Splice Site ENU
sa30864 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40542 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Sussman et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH slc4a4a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Renal tubular acidosis, proximal, with ocular abnormalities 604278
    DISEASE ASSOCIATED WITH slc4a4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function sodium:bicarbonate symporter activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003020 (1)
  • InterPro:IPR003024 (1)
  • InterPro:IPR011531 (1)
  • InterPro:IPR013769 (1)
  • InterPro:IPR016152 (1)
  • Pfam:PF00955 (1)
  • Pfam:PF07565 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc4a4a-001 (1) 2810
    ncRNA slc4a4a-002 (1) 499
    slc4a4a-003 (1) 542
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc4a4a No data available
    MARKER RELATIONSHIPS
    slc4a4aContained in: [BAC] CH211-72M2 (1) (order this), CH211-254O18 (1) (order this), DKEY-256M11 (1) (order this)
    [Fosmid] CH1073-449N9 (1) (order this)
    slc4a4aEncodes: [EST] ibd2520 (order this)
    [cDNA] MGC:193793 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034984 (1) 4739bp
    Genomic GenBank:BX294131 (1) 164141bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8PYB9 (1) 1114aa
    Sequence Clusters UniGene:80179 (1)
    Sequence Information (all 38)
    OTHER slc4a4a GENE PAGES
  • Alliance (1)
  • Gene:568631 (1)
  • VEGA:OTTDARG00000018582 (1)
  • Ensembl(GRCz11):ENSDARG00000013730 (2)
  • ORTHOLOGY for slc4a4a (Chr: 5)
    CITATIONS (39)