ZFIN is now using GRCz12tu for Genomic Data
Gene
phldb1a
- ID
- ZDB-GENE-060526-272
- Name
- pleckstrin homology-like domain, family B, member 1a
- Symbol
- phldb1a Nomenclature History
- Previous Names
-
- phldb1
- si:dkey-252h13.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be active in basal cortex. Human ortholog(s) of this gene implicated in osteogenesis imperfecta. Orthologous to human PHLDB1 (pleckstrin homology like domain family B member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Osteogenesis imperfecta, type XXIII | 620639 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000253 | Forkhead-associated (FHA) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR037810 | PHLDB1/2/3, PH domain |
| Family | IPR052212 | Pleckstrin homology-like domain-containing protein |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
phldb1a-201
(1)
|
Ensembl | 3,725 nt | ||
| mRNA |
phldb1a-202
(1)
|
Ensembl | 4,244 nt | ||
| mRNA |
phldb1a-203
(1)
|
Ensembl | 5,123 nt | ||
| mRNA |
phldb1a-204
(1)
|
Ensembl | 4,511 nt | ||
| mRNA |
phldb1a-205
(1)
|
Ensembl | 5,252 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers