ZFIN ID: ZDB-GENE-060526-262
Gene Name: transmembrane channel-like 2b
Gene Symbol: tmc2b
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-229d2.2

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ion channel activity and mechanosensitive ion channel activity; predicted to localize to the integral component of plasma membrane; orthologous to human TMC2 (transmembrane channel  ...
GENE EXPRESSION
All Expression Data: 2 figures from Maeda et al., 2014
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8817 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38469 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tmc2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tmc2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR012496 (1)
  • InterPro:IPR038900 (1)
  • Pfam:PF07810 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tmc2b-202 (1) 2359
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tmc2b
    MARKER RELATIONSHIPS
    tmc2bContained in: [BAC] DKEY-229D2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001302223 (1)
    Genomic GenBank:BX296526 (1) 179086bp
    Select Tool
    Polypeptide UniProtKB:F1QZE9 (1) 892aa
    Sequence Information (all 9)
    OTHER tmc2b GENE PAGES
  • Alliance (1)
  • Gene:567304 (1)
  • VEGA:OTTDARG00000017832 (1)
  • Ensembl(GRCz11):ENSDARG00000030311 (2)
  • ORTHOLOGY for tmc2b (Chr: 5)
    CITATIONS (17)