Gene

fer

ID
ZDB-GENE-060526-234
Name
fer (fps/fes related) tyrosine kinase
Symbol
fer Nomenclature History
Previous Names
  • si:dkey-190c14.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in blood vessel development; convergent extension involved in gastrulation; and erythrocyte development. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Is expressed in brain; head; intermediate cell mass of mesoderm; and pectoral fin. Orthologous to human FER (FER tyrosine kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fer Human Ortholog
No data available
Associated With fer Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000980 SH2 domain
Domain IPR001060 FCH domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR020635 Tyrosine-protein kinase, catalytic domain
Domain IPR031160 F-BAR domain
Domain IPR035849 Fes/Fps/Fer, SH2 domain
Domain IPR037452 Tyrosine-protein kinase Fer, F-BAR domain
Family IPR016250 Tyrosine-protein kinase, Fes/Fps type
Family IPR028539 Tyrosine-protein kinase Fer
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily F-BAR domain FCH domain Fes/Fps/Fer, SH2 domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain SH2 domain SH2 domain superfamily Tyrosine-protein kinase, active site Tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase Fer Tyrosine-protein kinase Fer, F-BAR domain Tyrosine-protein kinase, Fes/Fps type
UniProtKB:A0A2R8QR19 862
UniProtKB:F1QBS0 827
UniProtKB:F8W3J0 841
UniProtKB:A2CES6 842
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations