ZFIN ID: ZDB-GENE-060526-217
Gene Name: ataxin 2
Gene Symbol: atxn2
Previous Name: si:dkey-165i4.1 (1)
Location: Chr: 5 Details
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa870 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16931 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH atxn2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    amyotrophic lateral sclerosis type 13 Spinocerebellar ataxia 2 183090
    {Amyotrophic lateral sclerosis, susceptibility to, 13} 183090
    Parkinson's disease {Parkinson disease, late-onset, susceptibility to} 168600
    spinocerebellar ataxia type 2 Spinocerebellar ataxia 2 183090
    {Amyotrophic lateral sclerosis, susceptibility to, 13} 183090
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cytoplasmic mRNA processing body assembly (more)
    Cellular Component cytoplasmic stress granule (more)
    Molecular Function poly(A) RNA binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009604 (1)
  • InterPro:IPR009818 (1)
  • InterPro:IPR025852 (1)
  • Pfam:PF06741 (1)
  • Pfam:PF07145 (1)
  • Pfam:PF14438 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atxn2-001 (1) 4204
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM atxn2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atxn2Contained in: [BAC] DKEY-165I4 (1) (order this), DKEYP-30C3 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128349 (1) 3339bp
    Genomic GenBank:CR753867 (1) 125222bp
    Select Tool
    Polypeptide UniProtKB:A2CF31 (1) 1112aa
    Sequence Clusters UniGene:81390 (1)
    Sequence Information (all 22)
    OTHER atxn2 GENE PAGES
  • Gene:569210 (1)
  • VEGA:OTTDARG00000018538 (1)
  • Ensembl(GRCz10):ENSDARG00000052897 (1)
  • ORTHOLOGY for atxn2 (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human ATXN2 12
  • Gene:6311
  • OMIM:601517
  • HGNC:10555
  • Amino acid sequence comparison (1)
    Mouse Atxn2 5
  • MGI:1277223
  • Gene:20239
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (11)