Gene

atxn2

ID
ZDB-GENE-060526-217
Name
ataxin 2
Symbol
atxn2 Nomenclature History
Previous Names
  • si:dkey-165i4.1 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in regulation of cytoplasmic mRNA processing body assembly and stress granule assembly. Predicted to localize to cytoplasmic stress granule. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Orthologous to human ATXN2 (ataxin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Laboissonniere et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atxn2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Spinocerebellar ataxia 2 183090
{Amyotrophic lateral sclerosis, susceptibility to, 13} 183090
{Parkinson disease, late-onset, susceptibility to} 168600
Associated With atxn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009604 LsmAD domain
Domain IPR025852 Ataxin 2, SM domain
Domain IPR047575 Sm domain
Family IPR045117 Ataxin2-like
Domain Details Per Protein
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA atxn2-201 (1) Havana 4204 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations