ZFIN ID: ZDB-GENE-060526-202
Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 8a
Gene Symbol: adamts8a

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Attributions

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Previous Names: ADAMTS8d (1), si:dkey-127j5.2

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Brunet et al., 2015
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, eye, gut, heart (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13542 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14348 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40460 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adamts8a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular matrix (more)
    Molecular Function metalloendopeptidase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000884 (1)
  • InterPro:IPR001590 (1)
  • InterPro:IPR002870 (1)
  • InterPro:IPR010294 (1)
  • InterPro:IPR013273 (1)
  • InterPro:IPR013277 (1)
  • InterPro:IPR024079 (1)
  • PROSITE:PS50092 (1)
  • PROSITE:PS50215 (1)
  • Pfam:PF00090 (1)
  • Pfam:PF01421 (1)
  • Pfam:PF01562 (1)
  • Pfam:PF05986 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adamts8a-001 (1) 2653
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM adamts8a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    adamts8aContained in: [BAC] DKEY-127J5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_693015 (1) 5187bp
    Genomic GenBank:BX897688 (1) 70570bp
    Select Tool
    Polypeptide UniProtKB:A2BIA2 (1) 884aa
    Sequence Information (all 4)
    OTHER adamts8a GENE PAGES
  • Gene:569618 (1)
  • VEGA:OTTDARG00000017780 (1)
  • Ensembl(GRCz10):ENSDARG00000007709 (1)
  • ORTHOLOGY for adamts8a (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human ADAMTS8 11
  • Gene:11095
  • OMIM:605175
  • HGNC:224
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Adamts8 9
  • MGI:1353468
  • Gene:30806
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (12)