Gene

adamts8a

ID
ZDB-GENE-060526-202
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 8a
Symbol
adamts8a Nomenclature History
Previous Names
  • ADAMTS8d (1)
  • si:dkey-127j5.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to localize to extracellular matrix. Is expressed in several structures, including digestive system; eye; gonad; heart; and immune system. Orthologous to human ADAMTS8 (ADAM metallopeptidase with thrombospondin type 1 motif 8).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts8a Human Ortholog
No data available
Associated With adamts8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR010294 ADAM-TS Spacer 1
Domain IPR041645 ADAM cysteine-rich domain 2
Family IPR013273 ADAMTS/ADAMTS-like
Family IPR013277 Peptidase M12B, ADAM-TS8
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAM cysteine-rich domain 2 ADAMTS/ADAMTS-like ADAM-TS Spacer 1 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, ADAM-TS8 Peptidase M12B, propeptide Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A2BIA2 884
UniProtKB:A0A2R8QND5 457
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations