ZFIN ID: ZDB-GENE-060526-202
Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 8a
Gene Symbol: adamts8a
Previous Names: ADAMTS8d (1), si:dkey-127j5.2
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Brunet et al., 2015
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, eye, gut, heart (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa13542 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14348 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adamts8a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular matrix (more)
    Molecular Function metalloendopeptidase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000884 (1)
  • InterPro:IPR001590 (1)
  • InterPro:IPR002870 (1)
  • InterPro:IPR010294 (1)
  • InterPro:IPR013273 (1)
  • InterPro:IPR013277 (1)
  • InterPro:IPR024079 (1)
  • PROSITE:PS50092 (1)
  • PROSITE:PS50215 (1)
  • Pfam:PF00090 (1)
  • Pfam:PF01421 (1)
  • Pfam:PF01562 (1)
  • Pfam:PF05986 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adamts8a-001 (1) 2653
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adamts8a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    adamts8aContained in: [BAC] DKEY-127J5 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_693015 (1) 3710bp
    Genomic GenBank:BX897688 (1) 70570bp
    Select Tool
    Polypeptide UniProtKB:A2BIA2 (1) 884aa
    Sequence Information (all 4)
    OTHER adamts8a GENE PAGES 
  • Gene:569618 (1)
  • VEGA:OTTDARG00000017780 (1)
  • Ensembl(GRCz10):ENSDARG00000007709 (1)
  • ORTHOLOGY for adamts8a (Chr: 5) 
    Species Symbol Chromosome Accession # Evidence
    Human ADAMTS8 11
  • Gene:11095
  • OMIM:605175
  • HGNC:224
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Adamts8 9
  • MGI:1353468
  • Gene:30806
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (12)