ZFIN ID: ZDB-GENE-060526-18
Gene Name: dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Gene Symbol: dpagt1    Nomenclature History

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Previous Name: si:ch211-117m20.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity. Predicted to be involved in dolichyl diphosphate biosynthetic process. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ij and congenital myasthenic syndrome 13. Orthologous to human DPAGT1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1).
Genome Resources: Alliance (1),  Gene:566539 (1),  Ensembl(GRCz11):ENSDARG00000061061 (2)
GENE EXPRESSION
All Expression Data: 3 figures from DeRossi et al., 2016
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10435 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dpagt1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital disorder of glycosylation Ij Alliance Congenital disorder of glycosylation, type Ij 608093
    congenital myasthenic syndrome 13 Alliance Myasthenic syndrome, congenital, 13, with tubular aggregates 614750
    DISEASE ASSOCIATED WITH dpagt1 VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000715 Glycosyl transferase, family 4
    Family IPR033895 UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dpagt1-201 (1)    Ensembl 1295
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dpagt1 No data available
    MARKER RELATIONSHIPS
    dpagt1 Contained in: [BAC] CH211-117M20 (1)
    dpagt1 Encodes: [cDNA] MGC:162258 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089411 (1) 2190 bp
    Genomic GenBank:BX294376 (1) 178400 bp
    Select Tool
    Polypeptide UniProtKB:A2BFS6 (1) 406 aa
    Sequence Information (all 9)
    ORTHOLOGY for dpagt1 ( Chr: 5 )
    CITATIONS (20)