ZFIN ID: ZDB-GENE-060526-177
Gene Name: death-associated protein kinase 1
Gene Symbol: dapk1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: si:ch211-66i11.1, wu:fj09c03

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; protein phosphorylation; and signal transduction. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human DAPK1 (death associated protein kinase 1).
Genome Resources: Alliance (1),  Gene:558314 (1),  Ensembl(GRCz11):ENSDARG00000060093 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dapk1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH dapk1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process apoptotic process (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000488 Death domain
Domain IPR000719 Protein kinase domain
Domain IPR020683 Ankyrin repeat-containing domain
Domain IPR020859 Roc domain
Family IPR020676 Death-associated protein kinase 1
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011029 Death-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA dapk1-201 (1)    Ensembl 6320
ncRNA dapk1-002 (1)    Ensembl 697
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM dapk1 No data available
MARKER RELATIONSHIPS
dapk1 Contained in: [BAC] CH211-66I11 (1), DKEY-250N8 (1) (order this)
dapk1 Encodes: [EST] fj09c03
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001099990 (1) 4320 nt
Genomic RefSeq:NW_018394606 (1) Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8QS56 (1) 1477 aa
Sequence Information (all 19)
ORTHOLOGY for dapk1 ( Chr: 5 )
CITATIONS (21)