ZFIN ID: ZDB-GENE-060526-174
Gene Name: PR domain containing 8b
Gene Symbol: prdm8b    Nomenclature History

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Previous Name: si:ch211-57h10.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and nucleic acid binding activity. Predicted to be involved in oligodendrocyte development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in adaxial cell and nervous system. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 10. Orthologous to human PRDM8 (PR/SET domain 8).
Genome Resources: Alliance (1),  Gene:557162 (1),  Ensembl(GRCz11):ENSDARG00000054683 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16172 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31467 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-prdm8b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prdm8b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    progressive myoclonus epilepsy 10 Alliance ?Epilepsy, progressive myoclonic, 10 616640
    DISEASE ASSOCIATED WITH prdm8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prdm8b-201 (1)    Ensembl 2502
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prdm8b No data available
    MARKER RELATIONSHIPS
    prdm8b Contained in: [BAC] CH211-57H10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001105105 (1) 2502 nt
    Genomic GenBank:BX323826 (1) 119262 nt
    Select Tool
    Polypeptide UniProtKB:A2BG51 (1) 570 aa
    Sequence Information (all 9)
    ORTHOLOGY for prdm8b ( Chr: 5 )
    CITATIONS (19)