Gene
sftpbb
- ID
- ZDB-GENE-060526-155
- Name
- surfactant protein Bb
- Symbol
- sftpbb Nomenclature History
- Previous Names
-
- si:ch211-283h6.6
- wu:fd19f07
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have methyltransferase activity and nucleic acid binding activity. Predicted to be involved in methylation and sphingolipid metabolic process. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pulmonary alveolar proteinosis | Alliance | Surfactant metabolism dysfunction, pulmonary, 1 | 265120 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Saposin | Saposin B type domain | Saposin B type, region 2 | Saposin-like | Saposin-like type B, region 1 | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B8JK19
|
317 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
sftpbb-201
(1)
|
Havana | 1822 nt |
Interactions and Pathways
No data available
Plasmids
No data available