Gene

rusc2

ID
ZDB-GENE-060526-131
Name
RUN and SH3 domain containing 2
Symbol
rusc2 Nomenclature History
Previous Names
  • si:ch211-250o15.2 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to localize to cytoplasmic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive mental retardation 61. Is expressed in central nervous system. Orthologous to human RUSC2 (RUN and SH3 domain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rusc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder, autosomal recessive 61 617773
Associated With rusc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR004012 RUN domain
Domain IPR047342 AP-4 complex accessory subunit RUSC2, RUN domain
Family IPR047343 AP-4 complex accessory subunit RUSC1/2
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR037213 RUN domain superfamily
Domain Details Per Protein
Protein Length AP-4 complex accessory subunit RUSC1/2 AP-4 complex accessory subunit RUSC2, RUN domain RUN domain RUN domain superfamily SH3 domain SH3-like domain superfamily
UniProtKB:A0A8M2BCE1 1576
UniProtKB:A0A8M2BCI5 895
UniProtKB:A2BGP3 829
UniProtKB:A0A8M2BCE9 1642
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rusc2-201 (1) Havana 3257 nt
mRNA rusc2-202 (1) Ensembl 6770 nt
mRNA rusc2-203 (1) Ensembl 5535 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations