ZFIN ID: ZDB-GENE-060526-130
Gene Name: latent transforming growth factor beta binding protein 3
Gene Symbol: ltbp3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:ch211-247o20.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Involved in cardiac ventricle morphogenesis; outflow tract morphogenesis; and regulation of smooth muscle tissue development. Is expressed in heart primordium; notochord; pericardial region; pharyngeal arch; and pharyngeal mesoderm. Human ortholog(s) of this gene implicated in brachyolmia-amelogenesis imperfecta syndrome and geleophysic dysplasia 3. Orthologous to human LTBP3 (latent transforming growth factor beta binding protein 3).
Genome Resources: Alliance (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015669Tg Transgenic Insertion Unknown Unknown DNA
sa20482 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20483 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40507 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44612 Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ltbp3 N/A 1
    MO2-ltbp3 N/A 4
    DISEASE ASSOCIATED WITH ltbp3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    brachyolmia-amelogenesis imperfecta syndrome Alliance Dental anomalies and short stature 601216
    geleophysic dysplasia 3 Alliance Geleophysic dysplasia 3 617809
    DISEASE ASSOCIATED WITH ltbp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac ventricle morphogenesis (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ltbp3
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    TgBAC(-25ltbp3:TagRFP-Cre) ltbp3 CreTagRFP Danio rerio 1 5
    MARKER RELATIONSHIPS
    ltbp3 Contained in: [BAC] CH211-247O20 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:BX276181 (1) 39648 nt
    Select Tool
    ORTHOLOGY for ltbp3 ( Chr: 5 )
    CITATIONS (32)