ZFIN ID: ZDB-GENE-060526-109
Gene Name: tet methylcytosine dioxygenase 3
Gene Symbol: tet3    Nomenclature History

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Previous Name: si:ch211-220a11.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits methylcytosine dioxygenase activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endothelial to hematopoietic transition. Predicted to localize to nucleus. Is expressed in several structures, including cardiovascular system; eye; hematopoietic system; liver; and pleuroperitoneal region. Orthologous to human TET3 (tet methylcytosine dioxygenase 3).
Genome Resources: Alliance (1),  Gene:103283056 (1),  Ensembl(GRCz11):ENSDARG00000062646 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
au60 Indel Exon 6 Frameshift, Premature Stop TALEN
ihb2020 Insertion Exon 2 Unknown TALEN
mk18 Small Deletion Unknown Frameshift, Premature Stop TALEN
sa9686 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16660 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33552 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tet3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Beck-Fahrner syndrome 618798
    DISEASE ASSOCIATED WITH tet3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis involved in differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function methylcytosine dioxygenase activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tet3-201 (1)    Ensembl 3497
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tet3 No data available
    MARKER RELATIONSHIPS
    tet3 Contained in: [BAC] CH211-185J11 (1), CH211-220A11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001082905 (1)
    Genomic GenBank:CR388049 (1) 201176 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8Q4R6 (1) 2052 aa
    Sequence Information (all 20)
    ORTHOLOGY for tet3 ( Chr: 5 )
    CITATIONS (36)