ZFIN Gene: tet3

ZFIN ID: ZDB-GENE-060526-109

ZFIN ID: ZDB-GENE-060526-109

Gene Name:

tet methylcytosine dioxygenase 3

Gene Symbol:

tet3

Sequence Ontology ID :

SO:0000704

Previous Name:

si:ch211-220a11.1 (1)

Location:

Chr: 5 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Exhibits methylcytosine dioxygenase activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endothelial to ...

GENE EXPRESSION
All Expression Data:	9 figures from 7 publications
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
	brain dorsal aorta eye gill head head kidney common myeloid progenitor head kidney hematopoietic multipotent progenitor cell head kidney lymphocyte head kidney nucleate erythrocyte head kidney heart intermediate cell mass of mesoderm intestine kidney liver retinal ganglion cell layer retinal inner nuclear layer retinal outer nuclear layer spleen ventral wall of dorsal aorta whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
au60	Indel	Exon 6	Frameshift, Premature Stop	TALEN
ihb2020	Insertion	Exon 2	Unknown	TALEN
mk18	Small Deletion	Unknown	Frameshift, Premature Stop	TALEN
sa9686	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16660	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa33552	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE No data available

DISEASE ASSOCIATED WITH tet3 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH tet3 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cell morphogenesis involved in differentiation (more)
Cellular Component	nucleus (more)
Molecular Function	methylcytosine dioxygenase activity (more)

GO Terms (all 17)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR002857 (1) InterPro:IPR024779 (1) InterPro:IPR040175 (1)	PROSITE:PS51058 (1)	Pfam:PF02008 (1) Pfam:PF12851 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	tet3-201 (1)	3497	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM tet3 No data available

MARKER RELATIONSHIPS

tet3Contained in:

[BAC] CH211-185J11 (1) (order this), CH211-220A11 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001082905 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:CR388049 (1)	201176bp	Blast at MegaBLAST
Polypeptide	UniProtKB:A0A2R8Q4R6 (1)	2052aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 20)

OTHER tet3 GENE PAGES

Alliance (1)

Gene:103283056 (1)

VEGA:OTTDARG00000015864 (1)

Ensembl(GRCz11):ENSDARG00000062646 (2)

ORTHOLOGY for tet3 (Chr: 5)

CITATIONS (34)

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