Gene

thap1

ID
ZDB-GENE-060519-9
Name
THAP domain containing, apoptosis associated protein 1
Symbol
thap1 Nomenclature History
Previous Names
  • zgc:136597
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Zech et al., 2015
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With thap1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
torsion dystonia 6 Alliance Dystonia 6, torsion 602629
Associated With thap1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006612 THAP-type zinc finger
Family IPR026516 THAP domain-containing protein 1
Homologous_superfamily IPR038441 THAP-type zinc finger superfamily
Domain Details Per Protein
Protein Length THAP domain-containing protein 1 THAP-type zinc finger THAP-type zinc finger superfamily
UniProtKB:A0A0R4IRT9 158
UniProtKB:Q1JPT7 225
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations