header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-060519-9
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: THAP domain containing, apoptosis associated protein 1
Gene Symbol: thap1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:136597

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity. Predicted to localize to the nucleoplasm. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP  ...
GENE EXPRESSION
All Expression Data: Table S9 from Zech et al., 2015
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH thap1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
torsion dystonia 6 Dystonia 6, torsion 602629
DISEASE ASSOCIATED WITH thap1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell cycle (more)
Cellular Component nucleoplasm (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006612 (1)
  • InterPro:IPR026516 (1)
  • InterPro:IPR038441 (1)
    		•
  • PROSITE:PS50950 (1)
    		•
  • Pfam:PF05485 (1)
    		•
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM thap1 No data available
    MARKER RELATIONSHIPS
    thap1Encodes: [cDNA] MGC:136597 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045284 (1) 949bp
    Select Tool
    Genomic GenBank:FO904974 (1) 35850bp
    Select Tool
    Polypeptide UniProtKB:Q1JPT7 (1) 225aa
    Select Tool
    Sequence Clusters UniGene:80027 (1)
    Sequence Information (all 12)
    OTHER thap1 GENE PAGES
  • Alliance (1)
  • Gene:692315 (1)
  • Ensembl(GRCz11):ENSDARG00000059020 (2)
    • ORTHOLOGY for thap1 (Chr: 5)
    CITATIONS (17)